LOK rabbit pAb
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
STK10; LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase
UniProt
O94804
Swiss Prot
O94804
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human STK10. AA range:491-540
Target
LOK
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Molecular Weight
120kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
120kD
Fragment
IgG
Subcellular Location
Cell membrane ; Peripheral membrane protein .
Other Product Names
STK10; LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase
Gene ID (Human)
6793
Available Sizes
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