LASS4 rabbit pAb
Function: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner. similarity: Contains 1 homeobox DNA-binding domain. similarity: Contains 1 TLC (TRAM/LAG1/CLN8) domain.
Product Specifications
Background
UniProt
Q9HA82
Swiss Prot
Q9HA82
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human LASS4. AA range:41-90
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
46kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
46kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Other Product Names
CERS4; LASS4; Ceramide synthase 4; CerS4; LAG1 longevity assurance homolog 4
Gene ID (Human)
79603
Available Sizes
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