JIK rabbit pAb
Catalytic activity: ATP + a protein = ADP + a phosphoprotein. function: Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK. PTM: Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. similarity: Contains 1 protein kinase domain. subcellular location: Also localized to the peripheral cell membrane. subunit: Self-associates. tissue specificity: Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
Product Specifications
Background
Product Name Alternative
UniProt
Q9H2K8
Swiss Prot
Q9H2K8
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human TAOK3. AA range:531-580
Target
JIK
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Molecular Weight
110kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
110kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cell membrane ; Peripheral membrane protein . Also localized to the peripheral cell membrane.
Other Product Names
Gene ID (Human)
51347
Available Sizes
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