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IL-2 rabbit pAb

The protein encoded by this gene is a secreted Cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this Cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7) . The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]

Product Name Alternative

IL2; Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin

UniProt

P60568

Swiss Prot

P60568

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human IL-2. AA range:16-65

Target

IL-2

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

15kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

15kD

Fragment

IgG

Subcellular Location

Secreted.

Other Product Names

IL2; Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin

Gene ID (Human)

3558

Available Sizes

Curated Selection

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