HBP1 rabbit pAb
Function: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. similarity: Contains 1 AXH domain. similarity: Contains 1 HMG box DNA-binding domain. subunit: Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.
Product Specifications
Background
UniProt
O60381
Swiss Prot
O60381
Reactivity
Human; Mouse; Rat; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human HBP1. AA range:431-480
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
57kD
Storage Conditions
-20°C/1 year
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2495-1.pdf
Observed Molecular Weight
57kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1
Gene ID (Human)
26959
Available Sizes
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