GPR50 rabbit pAb
This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010],
Product Specifications
Background
Product Name Alternative
GPR50; Melatonin-related receptor; G protein-coupled receptor 50; H9
UniProt
Q13585
Swiss Prot
Q13585
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MTR1L. AA range:301-350
Target
GPR50
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
68kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
68kD
Fragment
IgG
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Other Product Names
GPR50; Melatonin-related receptor; G protein-coupled receptor 50; H9
Gene ID (Human)
9248
Available Sizes
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