FAST rabbit pAb
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
FASTK; Fas-activated serine/threonine kinase; FAST kinase
UniProt
Q14296
Swiss Prot
Q14296
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human FAST. AA range:361-410
Target
FAST
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
61kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
61kD
Fragment
IgG
Subcellular Location
[Isoform 4]: Mitochondrion matrix . Colocalizes with mitochondrial RNA granules. .
Other Product Names
FASTK; Fas-activated serine/threonine kinase; FAST kinase
Gene ID (Human)
10922
Available Sizes
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