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EOMES rabbit pAb

This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],

Product Specifications

Background

This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Product Name Alternative

EOMES; TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2

UniProt

O95936

Swiss Prot

O95936

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human EOMES. AA range:59-108

Target

EOMES

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

73kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

73kD

Fragment

IgG

Subcellular Location

Nucleus .

Other Product Names

EOMES; TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2

Gene ID (Human)

8320

Available Sizes

Curated Selection

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