EIF2Bγ rabbit pAb
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],
Product Specifications
Background
Product Name Alternative
EIF2B3; Translation initiation factor eIF-2B subunit gamma; eIF-2B GDP-GTP exchange factor subunit gamma
UniProt
Q9NR50
Swiss Prot
Q9NR50
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from eIF2Bγ . at AA range: 240-320
Target
EIF2Bγ
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
50kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
50kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex
Other Product Names
EIF2B3; Translation initiation factor eIF-2B subunit gamma; eIF-2B GDP-GTP exchange factor subunit gamma
Gene ID (Human)
8891
Available Sizes
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