DRAK2 rabbit pAb
Catalytic activity: ATP + a protein = ADP + a phosphoprotein. function: Acts as a positive regulator of apoptosis. PTM: Autophosphorylated. similarity: Belongs to the protein kinase superfamily. similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. similarity: Contains 1 protein kinase domain. subunit: Interacts with CHP causing CHP to translocate from the Golgi to the nucleus. tissue specificity: Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
Product Specifications
Background
UniProt
O94768
Swiss Prot
O94768
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human STK17B. AA range:251-300
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
45kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
45kD
Fragment
IgG
Subcellular Location
Nucleus . Cell membrane . Endoplasmic reticulum-Golgi intermediate compartment . Colocalizes with STK17B at the plasma membrane. .
Other Product Names
STK17B; DRAK2; Serine/threonine-protein kinase 17B; DAP kinase-related apoptosis-inducing protein kinase 2
Gene ID (Human)
9262
Available Sizes
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