Choactase rabbit pAb
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010],
Product Specifications
Background
Product Name Alternative
CHAT; Choline O-acetyltransferase; CHOACTase; ChAT; Choline acetylase
UniProt
P28329
Swiss Prot
P28329
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Choactase. AA range:334-383
Target
Choactase
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
82,70kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
82,70kD
Fragment
IgG
Subcellular Location
Nucleus, cytoplasm, cytosol, presynapse
Other Product Names
CHAT; Choline O-acetyltransferase; CHOACTase; ChAT; Choline acetylase
Gene ID (Human)
1103
Available Sizes
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