BRMS-1 rabbit pAb
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q9HCU9
Swiss Prot
Q9HCU9
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human BRMS1. AA range:21-70
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
28kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
28kD
Fragment
IgG
Subcellular Location
Nucleus. Cytoplasm. Predominantly nuclear.
Other Product Names
BRMS1; Breast cancer metastasis-suppressor 1
Gene ID (Human)
25855
Available Sizes
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