BCoR rabbit pAb
The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y. [provided by RefSeq, Jun 2010],
Product Specifications
Background
UniProt
Q6W2J9
Swiss Prot
Q6W2J9
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human BCOR. AA range:1231-1280
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
192kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
192kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
BCOR; KIAA1575; BCL-6 corepressor; BCoR
Gene ID (Human)
54880
Available Sizes
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