Bak rabbit pAb
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of Cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q16611
Swiss Prot
Q16611
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Bak. AA range:1-50
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Molecular Weight
25kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
25kD
Fragment
IgG
Subcellular Location
Mitochondrion outer membrane ; Single-pass membrane protein .
Other Product Names
BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7
Gene ID (Human)
578
Available Sizes
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