Arp3 rabbit pAb

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013],

Product Specifications

Background

Product Name Alternative

ACTR3; ARP3; Actin-related protein 3; Actin-like protein 3

UniProt

P61158

Swiss Prot

P61158

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human ACTR3. AA range:369-418

Target

Arp3

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

47kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

47kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton . Cell projection . Nucleus . In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes) (PubMed:19109554) .