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APHC rabbit pAb

Enzyme regulation: Activated by Ca (2+) and inhibited by Zn (2+). function: Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity. similarity: Belongs to the alkaline ceramidase family. tissue specificity: Ubiquitously expressed. Highest expression in placenta.

Product Specifications

Background

Enzyme regulation:Activated by Ca (2+) and inhibited by Zn (2+) ., function:Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity., similarity:Belongs to the alkaline ceramidase family., tissue specificity:Ubiquitously expressed. Highest expression in placenta.

Product Name Alternative

ACER3; APHC; PHCA; Alkaline ceramidase 3; AlkCDase 3; Alkaline CDase 3; Alkaline dihydroceramidase SB89; Alkaline phytoceramidase; aPHC

UniProt

Q9NUN7

Swiss Prot

Q9NUN7

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human PHCA. AA range:171-220

Target

APHC

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

35kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

35kD

Fragment

IgG

Subcellular Location

Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .

Other Product Names

ACER3; APHC; PHCA; Alkaline ceramidase 3; AlkCDase 3; Alkaline CDase 3; Alkaline dihydroceramidase SB89; Alkaline phytoceramidase; aPHC

Gene ID (Human)

55331

Available Sizes

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