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ABCC12 rabbit pAb

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12. 1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]

Product Name Alternative

ABCC12; MRP9; Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12

UniProt

Q96J65

Swiss Prot

Q96J65

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MRP9. AA range:691-740

Target

ABCC12

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

170kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

170kD

Fragment

IgG

Subcellular Location

Endoplasmic reticulum membrane ; Multi-pass membrane protein .

Other Product Names

ABCC12; MRP9; Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12

Gene ID (Human)

94160

Available Sizes

Curated Selection

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