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NBR1 Rabbit pAb

NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.

Product Specifications

Background

NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.

Product Name Alternative

1A13B, MIG19, Nbr1

UniProt

Q14596

Swiss Prot

Q14596

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein

Clonality

Polyclonal

Source

Rabbit

Applications

IHC

Concentration

1mg/mL

Dilution

IHC 1:100-200

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Molecular Weight

120kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

120kDa

Fragment

IgG

Subcellular Location

Cytoplasm, Cytoplasmic vesicle, Lysosome

Other Product Names

1A13B, MIG19, Nbr1

Gene ID (Human)

4077

Available Sizes

Curated Selection

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