VEGF Rabbit pAb
VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are associated with microvascular complications of diabetes type 1 (MVCD1). VEGFA has 17 isoforms with MW from 16 to 45 kDa. Some isoforms have homodimer forms (e. g. ; VEGFA189 38kDa or VEFGA110 34kDa). VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids (PMID: 15602010 ). This antibody can recognize all VEGFA isoforms.
Product Specifications
Background
Product Name Alternative
VEGFA antibody, VPF antibody, VEGF120 antibody, Vascular endothelial growth factor antibody
UniProt
P15692
Swiss Prot
P15692
Reactivity
Human, Rat, Mouse
Immunogen
Recombinant Protein
Clonality
Polyclonal
Source
Rabbit
Applications
IHC
Concentration
1mg/mL
Dilution
IHC 1:200-500
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
23,45kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
23,45kDa
Fragment
IgG
Subcellular Location
Secreted
Other Product Names
VEGFA antibody, VPF antibody, VEGF120 antibody, Vascular endothelial growth factor antibody
Gene ID (Human)
7422
Available Sizes
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