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P21 Rabbit pAb

P21 / WAF1 / CIP1 also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1 is a protein that in humans is encoded by the CDKN1A gene. p21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclin-CDK2, -CDK1, and -CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase.

Product Specifications

Background

P21 / WAF1 / CIP1 also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1 is a protein that in humans is encoded by the CDKN1A gene. p21 is a potent cyclin-dependent kinase inhibitor (CKI) . The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclin-CDK2, -CDK1, and -CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase.

Product Name Alternative

CDKN1 antibody, CDKI antibody, CDKN1A antibody, MDA 6 antibody, p21 cip1 antibody, p21waf antibody

UniProt

P38936

Swiss Prot

P38936

Reactivity

Human, Rat, Mouse

Immunogen

Recombinant Protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB, IHC

Concentration

1mg/mL

Dilution

WB 1:1,000-2,000 IHC 1:100-200

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Molecular Weight

21kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

21kDa

Fragment

IgG

Subcellular Location

Cytoplasm, Nucleus

Other Product Names

CDKN1 antibody, CDKI antibody, CDKN1A antibody, MDA 6 antibody, p21 cip1 antibody, p21waf antibody

Gene ID (Human)

1026

Available Sizes

Curated Selection

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