MeCP2 Rabbit pAb
Methyl-CpG-binding protein 2 (MeCP2), whose exact function is unclear. It appears to help regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein usually regulates genes involved in brain function, even though this protein is found throughout the body. Within the brain, the MeCP2 protein is important for the function of nerve cells (neurons) and is present in high levels in mature neurons. This protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. Many of the genes that are known to be regulated by the MeCP2 protein play a role in normal brain function, particularly the maintenance of synapses.
Product Specifications
Background
Product Name Alternative
Methyl CpG Binding Protein 2 ; RTS; AUTSX3; MRX16; MRX79; PPMX; RTT; Rett Syndrome; Mental Retardation, X-linked 16
UniProt
P51608
Swiss Prot
P51608
Reactivity
Human
Immunogen
Synthetic Peptide
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1mg/mL
Dilution
WB 1:2,000
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
53kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
53kDa
Fragment
IgG
Subcellular Location
Nucleus
Other Product Names
Methyl CpG Binding Protein 2 ; RTS; AUTSX3; MRX16; MRX79; PPMX; RTT; Rett Syndrome; Mental Retardation, X-linked 16
Gene ID (Human)
4204
Available Sizes
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