Caspase 9 Mouse mAb
Caspase-9 is an initiator caspase, encoded by the CASP9 gene. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP).
Product Specifications
Background
Product Name Alternative
APAF 3 antibody, Apoptosis related cysteine peptidase antibody, Apoptotic protease-activating factor 3 antibody, CASP 9 antibody
UniProt
P55211
Swiss Prot
P55211
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Source
Mouse
Applications
WB, IP, IF
Concentration
1mg/mL
Dilution
WB 1:1,000-5,000 IP 1:200 IF 1:100-200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
47 (51)kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
47 (51) kDa
Fragment
IgG1
Subcellular Location
Cytosol, Mitochondrion, Nucleus
Other Product Names
APAF 3 antibody, Apoptosis related cysteine peptidase antibody, Apoptotic protease-activating factor 3 antibody, CASP 9 antibody
Gene ID (Human)
842
Available Sizes
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