Prilocaine

Prilocaine, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects[1][2].

Product Specifications

CAS Number

[721-50-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Na+/K+ ATPase

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/prilocaine.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 2.5 mg/mL (ultrasonic)

Smiles

CC(NCCC)C(NC1=CC=CC=C1C)=O

Molecular Formula

C13H20N2O

Molecular Weight

220.31

Precautions

H302, H315, H319, H335

References & Citations

[1]M Mete, et al. Neurotoxic effects of local anesthetics on the mouse neuroblastoma NB2a cell line. Biotech Histochem. 2015 Apr;90 (3) :216-22.|[2]H Kutchai, et al. Effects of local anaesthetics on the activity of the Na, K-ATPase of canine renal medulla. Pharmacol Res. 2000 Jan;41 (1) :1-7.