Deltasonamide 2 (TFA)

Deltasonamide 2 TFA is competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM[1].

Product Specifications

CAS Number

[2235358-74-2]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/deltasonamide-2-tfa.html

Concentration

10mM

Purity

99.67

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=S(C1=CC=C(S(=O)(N(CC2=CC=C(Cl)C=C2)C3CCCC3)=O)C=C1)(N([C@H]4CC[C@H](N)CC4)CC5=NC(NC)=NC=C5)=O.O=C(O)C(F)(F)F

Molecular Formula

C32H40ClF3N6O6S2

Molecular Weight

761.27

References & Citations

[1]Klein CH, et al. PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell linesharboring oncogenic KRas. Int J Cancer. 2019 Feb 15;144 (4) :767-776.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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