Super-TDU

Super-TDU is a specific YAP antagonist targeting YAP-TEADs interaction. Super-TDU suppresses tumor growth in gastric cancer mouse model[1].

Product Specifications

CAS Number

[1599441-71-0]

UNSPSC

12352209

Target

YAP

Type

Peptides

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/super-tdu.html

Purity

99.65

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@@H](C)CC)C(NCC(NCC(N[C@@H](CO)C(NCC(N[C@@H](CC(N)=O)C(N5[C@@H](CCC5)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N6[C@@H](CCC6)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N7[C@@H](CCC7)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N8[C@@H](CCC8)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H](CC9=CC=CC=C9)C(N[C@@H](CC%10=CC=CC=C%10)C(N[C@@H](CCCCN)C(N%11[C@@H](CCC%11)C(N%12[C@@H](CCC%12)C(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N

Molecular Formula

C237H369N65O70S

Molecular Weight

5280.92

References & Citations

[1]Jiao S, et al. A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer. Cancer Cell. 2014 Feb 10;25 (2) :166-80.