KAC-50.1

KAC-50.1 is an α-Synuclein (α-syn) PET ligand, with a KD of 35 nM toward site 2 in recombinant α-syn fibrils[1].

Product Specifications

UNSPSC

12352005

Target

α-synuclein

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/kac-50-1.html

Smiles

COC1=CC=C(C=C1)/C=C/C2=CN(N=N2)C3=CC=CC=C3

Molecular Formula

C17H15N3O

Molecular Weight

277.32

References & Citations

[1]Dinahlee Saturnino Guarino, et al. Identification and In Vitro and In Vivo Characterization of KAC-50.1 as a Potential α-Synuclein PET Radioligand. ACS Chem Neurosci. 2024 Nov 20;15 (22) :4210-4219.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

α-synuclein

Curated Selection

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