KAC-50.1
KAC-50.1 is an α-Synuclein (α-syn) PET ligand, with a KD of 35 nM toward site 2 in recombinant α-syn fibrils[1].
Product Specifications
UNSPSC
12352005
Target
α-synuclein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kac-50-1.html
Smiles
COC1=CC=C(C=C1)/C=C/C2=CN(N=N2)C3=CC=CC=C3
Molecular Formula
C17H15N3O
Molecular Weight
277.32
References & Citations
[1]Dinahlee Saturnino Guarino, et al. Identification and In Vitro and In Vivo Characterization of KAC-50.1 as a Potential α-Synuclein PET Radioligand. ACS Chem Neurosci. 2024 Nov 20;15 (22) :4210-4219.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α-synuclein
Curated Selection
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