SJ26
Product Specifications
UNSPSC Description
SJ26 is a Wnt1 inhibitor with anticancer activity. SJ26 inhibits the expression of Wnt1 and Wnt1-mediated downstream signaling pathways in a G-quadruplex structure-dependent manner to suppress the migration activity of cancer cells[1].
Target Antigen
G-quadruplex; Wnt
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sj26.html
Smiles
O=C1C2=CC(Cl)=CC=C2C3=C1C4=C(C=CC=C4)N=C3N5CCC(CCCC6CCNCC6)CC5
Molecular Weight
474.04
References & Citations
[1]Liencheng Chang, et al. "Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validation." Oncotarget 7.42 (2016): 67986.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164528/SJ26-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164528/
Clinical Information
No Development Reported
CAS Number
1801288-67-4
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