Cyazofamid

Cyazofamid exerts its bactericidal effect by impairing ATP production. Cyazofamid inhibits organic cation transporter 3 (OCT3) and OAT1, with IC50 values of 1.54 and 17.3 μM, respectively[1][2][3].

Product Specifications

CAS Number

[120116-88-3]

Product Name Alternative

IKF-916

UNSPSC

12352005

Hazard Statement

H410

Target

OAT; Oct3/4

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cyazofamid.html

Purity

98.15

Solubility

DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N#CC1=NC(Cl)=C(N1S(=O)(N(C)C)=O)C2=CC=C(C)C=C2

Molecular Formula

C13H13ClN4O2S

Molecular Weight

324.79

Precautions

H410

References & Citations

[1]Song IS, et al. Interactions between cyazofamid and human drug transporters. J Biochem Mol Toxicol. 2020 Apr;34 (4) :e22459. |[2]Mitani S, et al. Biological properties of the novel fungicide cyazofamid against Phytophthora infestans on tomato and Pseudoperonospora cubensis on cucumber. Pest Manag Sci. 2002 Feb;58 (2) :139-45.|[3]Mitani, et al. "Antifungal activity of the novel fungicide cyazofamid against Phytophthora infestans and other plant pathogenic fungi in vitro." Pesticide biochemistry and physiology 70.2 (2001) : 92-99.