Raseglurant
Product Specifications
UNSPSC Description
Raseglurant (ADX-10059) is a mGlu5 receptor negative allosteric modulator. Raseglurant is effective against migraine. Raseglurant reduces the Haloperidol (HY-14538)-induced catalepsy in mice[1][2].
Target Antigen
mGluR
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/raseglurant.html
Smiles
NC1=C(C)C=C(C)N=C1C#CC2=CC=CC(F)=C2
Molecular Weight
240.28
References & Citations
[1]Romero-Fernandez W, et al. The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson's Disease. Mol Neurobiol. 2022 Oct;59(10):5955-5969. |[2]Font J, et al. Correction: Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. Elife. 2018 Jan 8;7:e34752.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14866/Raseglurant-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14866/
Clinical Information
Phase 2
CAS Number
757950-09-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Monoclonal Peroxiredoxin 4 Antibody (SAIC-40A-24) [Biotin]](https://cdn.genprice.uk/genprice/genprice4.png)
NBP3-20105B 0.1 mL
Rabbit Monoclonal Peroxiredoxin 4 Antibody (SAIC-40A-24) [Biotin]
Ask
View Details