Nilofabicin
Product Specifications
UNSPSC Description
Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin[1].
Target Antigen
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nilofabicin.html
Purity
99.58
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C(OCCC2=CC=CS2)C=CN1CC3=CC=CC(N)=C3C
Molecular Weight
340.44
References & Citations
[1]Jong Hwa Yum,et, al. In Vitro Activities of CG400549, a Novel FabI Inhibitor, against Recently Isolated Clinical Staphylococcal Strains in Korea. Antimicrob Agents Chemother. 2007 Jul; 51(7): 2591–2593.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111071/Nilofabicin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111071/Nilofabicin-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
934628-27-0
Available Sizes
Curated Selection
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