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SAR405

Selective ATP-competitive inhibitor of Vps34

Product Specifications

CAS Number

1523406-39-4

Product Name Alternative

(S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one

Field of Research

Ubiquitination Proteasome Autophagy

Purity

0.9803

Solubility

≥22.19 mg/mL in DMSO; insoluble in H2O; ≥32.25 mg/mL in EtOH with ultrasonic

Smiles

C[C@H]1N(C(N=C2N3CC[C@@H](C(F)(F)F)N2CC4=CN=CC(Cl)=C4)=CC3=O)CCOC1

Molecular Formula

C19H21ClF3N5O2

Molecular Weight

443.85

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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