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Semagacestat (LY450139)

γ-secretase inhibitor

Product Specifications

Product Name Alternative

(2S)-2-hydroxy-3-methyl-N-[(2S)-1-[[(5S)-3-methyl-4-oxo-2,5-dihydro-1H-3-benzazepin-5-yl]amino]-1-oxopropan-2-yl]butanamide

Sequence

LY-450139, LY 450139,Semagacestat

Field of Research

Neuroscience Alzheimer Neuroscience Amyloid β Proteases Gamma Secretase Neuroscience Gap Junction

Purity

0.994

Form

A solid

Solubility

insoluble in H2O; ≥18.05 mg/mL in DMSO; ≥40.3 mg/mL in EtOH with ultrasonic

Smiles

CC(C)C(C(=O)NC(C)C(=O)NC1C2=CC=CC=C2CCN(C1=O)C)O

Molecular Formula

C19H27N3O4

Molecular Weight

361.44

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

CAS Number

425386-60-3

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