GPI-1485

GPI-1485 (GM1485), a nonimmunosuppressive immunophilin ligand, promotes neurofunctional improvement and neural regeneration following stroke[1].

Product Specifications

CAS Number

[186268-78-0]

Product Name Alternative

GM1485

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

FKBP

Type

Reference compound

Related Pathways

Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/gpi-1485.html

Purity

99.56

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)[C@H]1N(C(C(C(C)(C)CC)=O)=O)CCC1

Molecular Formula

C12H19NO4

Molecular Weight

241.28

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

References & Citations

[1]Andrew F Ducruet , et al. GM1485, a Nonimmunosuppressive Immunophilin Ligand, Promotes Neurofunctional Improvement and Neural Regeneration Following Stroke. J Neurosci Res. 2012 Jul;90 (7) :1413-23.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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