TGP-377/421

TGP-377/421 (Targapre-miR-377/421) is a potent miR-377 and miR-421 inhibitor that binds a functional site in both miRNAs[1].

Product Specifications

CAS Number

[16752-89-9]

Product Name Alternative

Targapre-miR-377/421

UNSPSC

12352005

Target

MicroRNA

Type

Reference compound

Related Pathways

Epigenetics

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/tgp-377-421.html

Purity

98.17

Solubility

DMSO : 66.67 mg/mL (ultrasonic)

Smiles

NC1=CC=C2C(N=C(C3=CC=CC(C4=NC5=CC(N)=CC=C5N4)=C3)N2)=C1

Molecular Formula

C20H16N6

Molecular Weight

340.38

References & Citations

[1]Haniff HS, et al. Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions. Nat Chem. 2020 Oct;12 (10) :952-961.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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