SLM6031434
Product Specifications
UNSPSC Description
SLM6031434 is a highly selective sphingosine kinase 2 (SphK2) inhibitor with Kis of 0.4 μM, 0.5 μM, >20 μM, 22 μM for mSphK2, rSphK2, mSphK1 and rSphK1, respectively. SLM6031434 decrease Sphingosine 1-phosphate (S1P) levels in U937 monocytic leukemia cells. SLM6031434 has the potential for renal fibrosis research[1].
Target Antigen
SphK
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/slm6031434.html
Smiles
N=C(N1[C@H](C2=NC(C3=CC=C(OCCCCCCCC)C(C(F)(F)F)=C3)=NO2)CCC1)N
Molecular Weight
453.50
References & Citations
[1]Yugesh Kharel, et al. Sphingosine Kinase 2 Inhibition and Blood Sphingosine 1-Phosphate Levels. J Pharmacol Exp Ther. 2015 Oct;355(1):23-31.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-120268/SLM6031434-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-120268/
Clinical Information
No Development Reported
CAS Number
1897379-33-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS9010067 Inquire
Rabbit anti-Drosophila melanogaster (Fruit fly) mbo Polyclonal Antibody
Ask
View Details MBS6362328-01 0.1 mL
VAT1L, CT (VAT1L, KIAA1576, Synaptic vesicle membrane protein VAT-1 homolog-like) (MaxLight 405)
Ask
View Details 
MBS6362328-02 5x 0.1 mL
VAT1L, CT (VAT1L, KIAA1576, Synaptic vesicle membrane protein VAT-1 homolog-like) (MaxLight 405)
Ask
View Details 