Anti-TNBC agent-7
Anti-TNBC agent-7 (Compound 13c) possesses anticancer activity, serving as a molecular probe to recognize and regulate the signal transduction of the USP21/JAK2/STAT3 axis, exhibiting nanomolar-level cytotoxicity against MDA-MB-231 and HCC-1806 cancer cells, effectively combating triple-negative breast cancer (TNBC) [1].
Product Specifications
UNSPSC
12352005
Target
JAK; STAT
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anti-tnbc-agent-7.html
Smiles
COC1=CC(NC2=C(C=CC(F)=C2)C(NCCC3=CNC4=C(C=CC(F)=C34)F)=O)=CC(OC)=C1OC
Molecular Formula
C26H24F3N3O4
Molecular Weight
499.48
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158439/anti-TNBC-agent-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158439/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[9007-83-4]
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