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PI3K-IN-1

PI3K-IN-1 (XL-147 derivative 1) is a potent inhibitor of PI3K. PI3K-IN-1 (25 μM) blocks PI3K/Akt signaling pathways[1].

Product Specifications

CAS Number

[1349796-36-6]

Product Name Alternative

XL-147 derivative 1

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/PI3K-IN-1.html

Purity

99.93

Solubility

DMSO : 27.5 mg/mL (ultrasonic; warming)

Smiles

COC1=CC(NC2=NC3=CC=CC=C3N=C2NS(C4=CC=C(C=C4)NC(C5=CC=C(C(OC)=C5)C)=O)(=O)=O)=CC(OC)=C1

Molecular Formula

C31H29N5O6S

Molecular Weight

599.66

Precautions

H315, H319, H320

References & Citations

[1]Mingyu Hao, et al. Exploring the Role of SRC in Extraocular Muscle Fibrosis of the Graves' Ophthalmopathy. Front Bioeng Biotechnol. 2020 May 8;8:392.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PI3K

Available Sizes

Curated Selection

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