PNU‐142721
Product Specifications
UNSPSC Description
PNU-142721 is a reverse transcriptase inhibitor and PXR agonist that effectively inhibits various type I HIV variants[1].
Target Antigen
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pnu-142721.html
Smiles
NC1=NC(S[C@H](C2=CC3=C(OC=C3)C=N2)C)=NC(Cl)=C1
Molecular Weight
306.77
References & Citations
[1]Cheng Y, et al. Activation of the human nuclear xenobiotic receptor PXR by the reverse transcriptase‐targeted anti‐HIV drug PNU‐142721[J]. Protein Science, 2011, 20(10): 1713-1719.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15380/PNU-142721-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15380/
Clinical Information
Phase 1
CAS Number
185220-03-5
Curated Selection
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