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PNU‐142721

PNU-142721 is a reverse transcriptase inhibitor and PXR agonist that effectively inhibits various type I HIV variants[1].

Product Specifications

CAS Number

[185220-03-5]

UNSPSC

12352005

Target

HIV; Reverse Transcriptase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/pnu-142721.html

Smiles

NC1=NC(S[C@H](C2=CC3=C(OC=C3)C=N2)C)=NC(Cl)=C1

Molecular Formula

C13H11ClN4OS

Molecular Weight

306.77

References & Citations

[1]Cheng Y, et al. Activation of the human nuclear xenobiotic receptor PXR by the reverse transcriptase‐targeted anti‐HIV drug PNU‐142721[J]. Protein Science, 2011, 20 (10) : 1713-1719.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Curated Selection

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