PNU‐142721
PNU-142721 is a reverse transcriptase inhibitor and PXR agonist that effectively inhibits various type I HIV variants[1].
Product Specifications
CAS Number
[185220-03-5]
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pnu-142721.html
Smiles
NC1=NC(S[C@H](C2=CC3=C(OC=C3)C=N2)C)=NC(Cl)=C1
Molecular Formula
C13H11ClN4OS
Molecular Weight
306.77
References & Citations
[1]Cheng Y, et al. Activation of the human nuclear xenobiotic receptor PXR by the reverse transcriptase‐targeted anti‐HIV drug PNU‐142721[J]. Protein Science, 2011, 20 (10) : 1713-1719.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Curated Selection
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