Cloxiquine (Standard)
Product Specifications
UNSPSC Description
Cloxiquine (Standard) is the analytical standard of Cloxiquine. This product is intended for research and analytical applications. Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ[1][2].
Target Antigen
Bacterial; Fungal; Parasite; PPAR
Type
Reference Standards
Related Pathways
Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/cloxiquine-standard.html
Smiles
OC1=C2N=CC=CC2=C(Cl)C=C1
Molecular Weight
179.60
References & Citations
[1]Latosińska JN, et al. Supramolecular synthon pattern in solid clioquinol and cloxiquine (APIs of antibacterial, antifungal, antiaging and antituberculosis drugs) studied by <sup>35</sup>Cl NQR, <sup>1</sup>H-<sup>17</sup>O and <sup>1</sup>H-<sup>14</sup>N NQDR and DFT/QTAIM. J Mol Model. 2011 Jul;17(7):1781-800.|[2]Zhang W, et, al. Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPARγ. Cell Death Dis. 2019 May 28;10(6):404.|[3]Hongmanee P, et, al. In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2007 Mar;51(3):1105-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0963R/Cloxiquine-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0963R/
CAS Number
130-16-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items