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Cloxiquine (Standard)

Product Specifications

UNSPSC Description

Cloxiquine (Standard) is the analytical standard of Cloxiquine. This product is intended for research and analytical applications. Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ[1][2].

Target Antigen

Bacterial; Fungal; Parasite; PPAR

Type

Reference Standards

Related Pathways

Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/cloxiquine-standard.html

Smiles

OC1=C2N=CC=CC2=C(Cl)C=C1

Molecular Weight

179.60

References & Citations

[1]Latosińska JN, et al. Supramolecular synthon pattern in solid clioquinol and cloxiquine (APIs of antibacterial, antifungal, antiaging and antituberculosis drugs) studied by <sup>35</sup>Cl NQR, <sup>1</sup>H-<sup>17</sup>O and <sup>1</sup>H-<sup>14</sup>N NQDR and DFT/QTAIM. J Mol Model. 2011 Jul;17(7):1781-800.|[2]Zhang W, et, al. Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPARγ. Cell Death Dis. 2019 May 28;10(6):404.|[3]Hongmanee P, et, al. In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2007 Mar;51(3):1105-6.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-B0963R/Cloxiquine-Standard-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-B0963R/

CAS Number

130-16-5

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