Cdc7-IN-21
Product Specifications
UNSPSC Description
Cdc7-IN-21 (compound 10c) is a potent and selective Cdc7 inhibitor with an IC50 of 0.07 nM. Cdc7-IN-21 can be used to study cancer[1].
Target Antigen
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdc7-in-21.html
Solubility
10 mM in DMSO
Smiles
O=C1N=C(CN2CCCC2)NC3=C1SC(C4=CNN=C4C)=C3
Molecular Weight
315.39
References & Citations
[1]Kurasawa O, et al. 2-Aminomethylthieno [3, 2-d] pyrimidin-4 (3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase[J]. Bioorganic & Medicinal Chemistry, 2017, 25(14): 3658-3670.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117677/Cdc7-IN-21-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117677/
Clinical Information
No Development Reported
CAS Number
1330781-04-8
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