PTH (39-84) (human)

PTH (39-84) (human) is the C-terminal fragment of parathyroid hormone (PTH) . pTH (39-84) (human) increases Apoptosis. pTH (39-84) (human) can stimulate osteoclast formation[1][2].

Product Specifications

CAS Number

[90880-43-6]

UNSPSC

12352209

Target

Apoptosis; Thyroid Hormone Receptor

Type

Peptides

Related Pathways

Apoptosis; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/pth-39-84-human.html

Purity

98.88

Solubility

H2O : ≥ 100 mg/mL

Smiles

O=C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(NCC(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C211H357N67O72

Molecular Weight

4984.50

References & Citations

[1]Divieti P, et al. Human PTH- (7-84) inhibits bone resorption in vitro via actions independent of the type 1 PTH/PTHrP receptor. Endocrinology. 2002 Jan;143 (1) :171-6.|[2]Divieti P, et al. Receptors for the carboxyl-terminal region of pth (1-84) are highly expressed in osteocytic cells. Endocrinology. 2001 Feb;142 (2) :916-25.