Lenalidomide-I
Lenalidomide-I (Compound 72), an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, is used in the recruitment of CRBN protein. Lenalidomide-I can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC BET degrader QCA570 (HY-112609) [1].
Product Specifications
CAS Number
[2207541-30-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lenalidomide-i.html
Purity
99.90
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(C(N(CC1=C2C=CC=C1I)C2=O)CC3)NC3=O
Molecular Formula
C13H11IN2O3
Molecular Weight
370.14
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
SULT2A1 (Bile salt Sulfotransferase, Dehydroepiandrosterone Sulfotransferase, DHEA-ST, Hydroxysteroid Sulfotransferase, HST, ST2, ST2A3, Sulfotransferase 2A1, ST2A1, HST, STD) discontinued
SULT2A1 (Bile salt Sulfotransferase, Dehydroepiandrosterone Sulfotransferase, DHEA-ST, Hydroxysteroid Sulfotransferase, HST, ST2, ST2A3, Sulfotransferase 2A1, ST2A1, HST, STD) discontinued
