TBTC
Product Specifications
UNSPSC Description
TBTC is a selective agonist with the activity of improving behavioral deficits in Alzheimer's disease model mice. TBTC can effectively activate the heterodimerization of RXRα with LXRα or PPARγ. TBTC stimulates the expression of apoE, ABCA1, and ABCG1 genes and reduces Aβ content in cells and animal models[1].
Target Antigen
RAR/RXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tbtc.html
Smiles
O=C(OC)C1=C(SC2=C1CCC(C2)C(C)(C)C)N
Molecular Weight
267.39
References & Citations
[1]Small molecule TBTC as a new selective retinoid X receptor α agonist improves behavioral deficit in Alzheimer's disease model mice
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121671/TBTC-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121671/
Clinical Information
No Development Reported
CAS Number
213192-26-8
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2142011-01 0.1 mL
HRP-Linked Monoclonal Antibody to HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA)
Ask
View Details