Catalpol

Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects[1][2][3].

Product Specifications

CAS Number

[2415-24-9]

Product Name Alternative

Catalpinoside

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HBV

Type

Natural Products

Related Pathways

Anti-infection

Field of Research

Cancer; Infection; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Catalpol.html

Concentration

10mM

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 7.14 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC[C@@]12[C@]([C@@H]3O[C@]([C@@H]([C@@H](O)[C@@H]4O)O)([H])O[C@@H]4CO)([H])[C@](C=CO3)([H])[C@H](O)[C@@H]1O2

Molecular Formula

C15H22O10

Molecular Weight

362.33

Precautions

H302, H315, H319, H335

References & Citations

[1]Jili Zhu, et al. Catalpol protects mice against renal ischemia/reperfusion injury via suppressing PI3K/Akt-eNOS signaling and inflammation. Int J Clin Exp Med. 2015 Feb 15;8 (2) :2038-44.|[2]M Yamazaki, et al. Neuritogenic effect of natural iridoid compounds on PC12h cells and its possible relation to signaling protein kinases. Biol Pharm Bull. 1996 Jun;19 (6) :791-5.|[3]R Mehrotra, et al. In vitro studies on the effect of certain natural products against hepatitis B virus. Indian J Med Res. 1990 Apr;92:133-8.