LY231617

LY231617 is a potent and blood-brain barrier penetrable antioxidant. LY231617 is a neuroprotective agent in brain, it can be used for the research of nervous disease[1][2].

Product Specifications

CAS Number

[141545-89-3]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ly231617.html

Concentration

10mM

Purity

98.13

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

OC1=C(C(C)(C)C)C=C(CNCC)C=C1C(C)(C)C.[H]Cl

Molecular Formula

C17H30ClNO

Molecular Weight

299.88

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Fuson KS, et al. Characterization of LY231617 protection against hydrogen peroxide toxicity. J Neurochem. 1999 Mar;72 (3) :1154-60.|[2]Clemens JA, et al. The antioxidant LY231617 reduces global ischemic neuronal injury in rats. Stroke. 1993 May;24 (5) :716-22; discussion 722-3.