TQS
TQS is a α7 nicotinic acetylcholine receptor (nAChR) positive allosteric modulator. TQS can be used for the research of neuroinflammatory pain[1].
Product Specifications
CAS Number
[353483-92-8]
UNSPSC
12352005
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tqs.html
Concentration
10mM
Purity
99.84
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=S(N)(C1=CC=C2NC(C3CC=CC3C2=C1)C4=CC=CC5=C4C=CC=C5)=O
Molecular Formula
C22H20N2O2S
Molecular Weight
376.47
References & Citations
[1]Abbas M, et al. The α7 nicotinic acetylcholine receptor positive allosteric modulator attenuates lipopolysaccharide-induced activation of hippocampal IκB and CD11b gene expression in mice. Drug Discov Ther. 2017;11 (4) :206-211.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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