MEK-IN-6
Product Specifications
UNSPSC Description
MEK-IN-6 (Example 69) is a MEK inhibitor. MEK-IN-6 inhibits ERK1/2 (Thr202/Tyr204) phosphorylation in A375 cells (IC50: 2 nM). MEK-IN-6 can be used for research of cancer[1].
Target Antigen
ERK; MEK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mek-in-6.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C2C(C(N(CC2)OCCO)=O)=C(N1C)NC3=CC=C(C=C3F)SC
Molecular Weight
393.43
References & Citations
[1]Shelley Allen, et al. 3,4-dihydro-2,7-naphthyridine-1,6(2h,7h)-diones as mek inhibitors. Patent. WO2022208391.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153445/MEK-IN-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153445/MEK-IN-6-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2845151-86-0
Available Sizes
Curated Selection
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