BODIPY FL thalidomide
BODIPY FL thalidomide is a high-affinity fluorescent probe for human cereblon protein with a Kd value of 3.6 nM[1].
Product Specifications
CAS Number
[2740620-18-0]
UNSPSC
12352005
Target
Fluorescent Dye; Ligands for E3 Ligase
Type
Reference compound
Related Pathways
Others; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bodipy-fl-thalidomide.html
Purity
99.18
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(COC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)NCCCCCCCCNC(CCC4=CC=C5C=C6C(C)=CC(C)=[N]6[B+3]([F-])([N-]54)[F-])=O
Molecular Formula
C37H43BF2N6O7
Molecular Weight
732.58
References & Citations
[1]Lin W, et al. Development of BODIPY FL Thalidomide As a High-Affinity Fluorescent Probe for Cereblon in a Time-Resolved Fluorescence Resonance Energy Transfer Assay. Bioconjug Chem. 2020 Nov 18;31 (11) :2564-2575.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Curated Selection
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